Symbol
Name
ID

Gata4
GATA binding protein 4
MGI:95664

Phenotype annotations related to reproductive system

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Mouse Phenotypes

reproductive system phenotype

oligozoospermia

abnormal spermatid morphology

decreased male germ cell number

multinucleated giant male germ cells

increased male germ cell apoptosis

decreased sperm progressive motility

asthenozoospermia

decreased seminal vesicle weight

ovarian follicular cyst

decreased ovary weight

small ovary

ovary cyst

abnormal seminiferous tubule epithelium morphology

abnormal Sertoli cell morphology

seminiferous tubule degeneration

abnormal fetal Leydig cell differentiation

decreased testis weight

small testis

testicular atrophy

abnormal ovary physiology

abnormal Sertoli cell barrier function

abnormal endometrium morphology

decreased uterus weight

abnormal spermatogenesis

abnormal primary sex determination

primary sex reversal

true hermaphroditism

delayed sexual maturation

delayed estrous cycle

decreased superovulation rate

failure of superovulation

female infertility

reduced female fertility

decreased litter size

reduced male fertility

Availability

Mouse Genotype

Gata4^em1Vigr/Gata4^em1Vigr

Gata4^tm1.1Jmol/Gata4^tm1.1Jmol

Gata4^tm1Sho/Gata4^tm1Sho

Gata4^tm1.2Wtp/Gata4⁺

Gata4^tm1Sho/Gata4⁺

Gata4^tm1.1Sad/Gata4^tm1.1Sad
Amhr2^tm3(cre)Bhr/Amhr2⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23